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DVL1 cDNA (ANA11070)

1ug
$189.00
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Gene Symbol:
DVL1
NCBI Gene Id:
1855
Alias Symbols:
DVL, DVL1L1, MGC54245
Protein Name:
Segment polarity protein dishevelled homolog DVL-1
Description of Target:
DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
Swissprot Id:
O14640
Protein Accession #:
NP_004412
Nucleotide Accession #:
BC050454
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express DVL1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express DVL1.
Tag:
None
Protein Interactions:
NCK2; TRIM69; NUMA1; HUWE1; UBC; DVL2; WWOX; SIPA1; PSMA3; LRRK2; ITCH; HECW1; NEDD4; ANXA7; SDC4; NKD2; CYLD; SIRT1; CCDC88C; VANGL1; CXXC4; PPM1A; DYNLT1; HDHD2; BRD7; DAAM1; AXIN1; USP13; SMAD3; SMAD7; FRAT1; RAC1; DVL3; SMAD2; DVL1; SMAD4; CSNK1D; CSN
Reconstitution and Storage:
Centrifuge the vials after receiving and add 5 μl ddH2O
Datasheets/Manuals:
Printable datasheet for anti-DVL1 (ANA11070) antibody

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