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Datasheets/Manuals | Printable datasheet for anti-DVL1 (ARP32101_T100-FITC) antibody |
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Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Yeast |
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Product Format | Liquid. Purified antibody supplied in 1x PBS buffer. |
Clonality | Polyclonal |
Host | Rabbit |
Conjugation | FITC: Fluorescein Isothiocyanate |
Application | WB |
Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
Immunogen | The immunogen is a synthetic peptide directed towards the C terminal region of human DVL1 |
Predicted Homology Based on Immunogen Sequence | Cow: 86%; Dog: 86%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 93%; Rat: 86%; Yeast: 85% |
Peptide Sequence | Synthetic peptide located within the following region: AAGAGGSGSESDHTAPSGVGSSWRERPAGQLSRGSSPRSQASATAPGLPP |
Concentration | 0.5 mg/ml |
Blocking Peptide | For anti-DVL1 (ARP32101_T100-FITC) antibody is Catalog # AAP32101 (Previous Catalog # AAPP03018) |
Sample Type Confirmation | DVL1 is supported by BioGPS gene expression data to be expressed in K562 |
Reference | Mizutani,K., (2005) Am. J. Clin. Oncol. 91 (6), 546-551 |
Gene Symbol | DVL1 |
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Gene Full Name | Dishevelled, dsh homolog 1 (Drosophila) |
Alias Symbols | DVL, DRS2, DVL1L1, DVL1P1 |
NCBI Gene Id | 1855 |
Protein Name | Segment polarity protein dishevelled homolog DVL-1 |
Description of Target | DVL1 is a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 gene is a candidate for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1 gene. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. Three transcript variants encoding three different isoforms have been found for this gene. |
Uniprot ID | O14640-2 |
Protein Accession # | NP_004412 |
Nucleotide Accession # | NM_004421 |
Protein Size (# AA) | 670 |
Molecular Weight | 73kDa |
Protein Interactions | NCK2; TRIM69; NUMA1; HUWE1; UBC; DVL2; WWOX; SIPA1; PSMA3; LRRK2; ITCH; HECW1; NEDD4; ANXA7; SDC4; NKD2; CYLD; SIRT1; CCDC88C; VANGL1; CXXC4; PPM1A; DYNLT1; HDHD2; BRD7; DAAM1; AXIN1; USP13; SMAD3; SMAD7; FRAT1; RAC1; DVL3; SMAD2; DVL1; SMAD4; CSNK1D; CSN |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "DVL1 Antibody - C-terminal region : FITC (ARP32101_T100-FITC)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Yeast".
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How long will it take to receive "DVL1 Antibody - C-terminal region : FITC (ARP32101_T100-FITC)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
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What buffer format is "DVL1 Antibody - C-terminal region : FITC (ARP32101_T100-FITC)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "DVL1 Antibody - C-terminal region : FITC (ARP32101_T100-FITC)"?
This target may also be called "DVL, DRS2, DVL1L1, DVL1P1" in publications.
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What is the shipping cost for "DVL1 Antibody - C-terminal region : FITC (ARP32101_T100-FITC)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "DVL1 Antibody - C-terminal region : FITC (ARP32101_T100-FITC)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "DVL1 Antibody - C-terminal region : FITC (ARP32101_T100-FITC)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "73kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "DVL1 Antibody - C-terminal region : FITC (ARP32101_T100-FITC)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "DVL1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "DVL1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "DVL1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "DVL1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "DVL1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "DVL1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.