DUSP6 Recombinant Protein (OPCD02819)

Catalog No: OPCD02819

DUSP6 Recombinant Protein (OPCD02819) using SDS-PAGE

DUSP6 Recombinant Protein (OPCD02819) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Met1-Ser300
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: DUSP6
• Gene Full Name: dual specificity phosphatase 6
• Alias Symbols: dual specificity protein phosphatase 6;dual specificity protein phosphatase PYST1;HH19;MAP kinase phosphatase 3;mitogen-activated protein kinase phosphatase 3;MKP3;PYST1;serine/threonine specific protein phosphatase.
• NCBI Gene Id: 1848
• Protein Name: Dual specificity protein phosphatase 6
• Description of Target: Inactivates MAP kinases. Has a specificity for the ERK family (PubMed:9858808). Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia (By similarity). Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain (By similarity).
• Uniprot ID: Q16828
• Protein Accession #: NP_001937.2
• Nucleotide Accession #: NM_001946.3
• Protein Size (# AA): Met1~Ser300
• Molecular Weight: 37kDa