DSTN Antibody - middle region (OAAB05780)

Catalog No: OAAB05780

Size:400UL

Western blot analysis of DSTN Antibody (Center) in MCF-7 cell lysates (35ug/lane). DSTN (arrow) was detected using the purified Pab.

Western blot analysis of DSTN (arrow) using rabbit polyclonal DSTN Antibody (Center) either nontransfected (Lane 1) or lysates transiently transfected transfected (Lane 2) with the DSTN gene.

DSTN is strongly supported by BioGPS gene expression data to be expressed in MCF7

Formalin-fixed and paraffin-embedded human brain tissue reacted with DSTN Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

DSTN Antibody (Center) flow cytometry analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Bovine|Human|Mouse|Porcine|Rat
• Product Format: Liquid PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: FC,IHC-P,WB
• Additional Information: Tissue Location: Widely distributed in various tissues.
• Reconstitution and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This DSTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the Central region of human DSTN.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Predicted Homology Based on Immunogen Sequence: Bovine, Mouse, Pig, Rat
• Concentration: 0.29 mg/ml
• Sample Type Confirmation:

  DSTN is strongly supported by BioGPS gene expression data to be expressed in MCF7

• Application Info: WB: 1:1000
  IHC-P: 1:50~100
  FC: 1:10~50
• Other Applications Image 1 Data: DSTN Antibody (Center) flow cytometry analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Target Info

• Gene Symbol: DSTN
• Alias Symbols: 2610043P17Rik, ACTDP, actin-depolymerizing factor, AD, ADF, AU042046, bA462D18.2, bA462D18.2 (destrin (actin depolymerizing factor ADF) (ACTDP)), co, corn1, corneal disease 1, destrin, Dsn, epididymis luminal protein 32, epididymis secretory sperm binding protein, HEL32, sid, sid 23, sid23p.
• NCBI Gene Id: 11034|445516|502674|513267|56431
• Protein Name: Destrin|destrin isoform a [Homo sapiens]|destrin isoform b [Homo sapiens]
• Description of Target: Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner.
• Uniprot ID: P60981|P60982|Q5E9D5|Q7M0E3|Q9R0P5
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_001011546.1,NP_006861.1
• Molecular Weight: 18506