Size:100 ul
$329.00
In Stock
SKU
OAGA00185
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More Information
Predicted Species Reactivity Human
Product Format Liquid
Clonality Polyclonal
Isotype IgG
Host Rabbit
Application ICC, IF, IHC-FFPE, WB
Additional Information Background: Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq]
:: Positive Controls: 293T, H1299, Molt-4
:: Cellular Localization: Cell membrane, Cell junction, desmosome
Reconstitution and Storage Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Replacement Item This antibody may replace item sc-135815 from Santa Cruz Biotechnology.
Immunogen Recombinant fragment corresponding to a region within amino acids 1 and 206 of Desmoglein 2 (Uniprot ID#Q14126)
Purification Purified by antigen-affinity chromatography.
Concentration 1 mg/ml
Datasheets/Manuals Printable datasheet for anti-DSG2 antibody - OAGA00185
Application Info Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)], ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Gene Symbol DSG2
Official Gene Full Name Desmoglein-2
Alias Symbols ARVC10 antibody, ARVD10 antibody, CDHF5 antibody, CMD1BB antibody, HDGC antibody, MGC117034 antibody, MGC117036 antibody, MGC117037 antibody, DSG2 antibody, cadherin family member 5 antibody, desmoglein-2 antibody, desmoglein 2 antibody
NCBI Gene Id 1829
Protein Name Desmoglein-2
Swissprot Id Q14126
Protein Accession # NP_001934.2
Molecular Weight 122 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express DSG2.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express DSG2.
  1. What is the species homology for "DSG2 Antibody (OAGA00185)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "DSG2 Antibody (OAGA00185)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "DSG2 Antibody (OAGA00185)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "DSG2 Antibody (OAGA00185)"?

    This target may also be called "ARVC10 antibody, ARVD10 antibody, CDHF5 antibody, CMD1BB antibody, HDGC antibody, MGC117034 antibody, MGC117036 antibody, MGC117037 antibody, DSG2 antibody, cadherin family member 5 antibody, desmoglein-2 antibody, desmoglein 2 antibody" in publications.

  5. What is the shipping cost for "DSG2 Antibody (OAGA00185)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "DSG2 Antibody (OAGA00185)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "DSG2 Antibody (OAGA00185)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "122 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "DSG2 Antibody (OAGA00185)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "DSG2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "DSG2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "DSG2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "DSG2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "DSG2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "DSG2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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