DSG2 Antibody - middle region (OASG02249)

Catalog#: OASG02249

• Size: 100 uL

• Predicted Species Reactivity: Human
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, ELISA
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Gene Symbol: DSG2
• Official Gene Full Name: desmoglein 2
• NCBI Gene Id: 1829;
• Swissprot Id: Q14126
• Alias Symbols: DSG2, CDHF5, Desmoglein-2, Cadherin family member 5, HDGC
• Replacement Item: This antibody may replace item sc-135815 from Santa Cruz Biotechnology.
• Description of Target: This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.
• Molecular Weight: 140 kDa
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• RNA Seq: Find tissues and cell lines supported by RNA-seq analysis to express DSG2.
• Immunogen: Synthesized peptide derived from the Internal region of human Dsg2. Location: 370-450aa.
• Concentration: 1 mg/ml
• Specificity: Dsg2 Polyclonal Antibody detects endogenous levels of Dsg2 protein.
• Application Info: WB 1:500-1:2000; ELISA 1:40000;

Protocol:

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