- Predicted Species Reactivity:
- Human
- Product Format:
- Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Host:
- Rabbit
- Application:
- WB, ELISA
- Reconstitution and Storage:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Official Gene Full Name:
- desmoglein 2
- NCBI Gene Id:
- 1829;
- Alias Symbols:
- DSG2, CDHF5, Desmoglein-2, Cadherin family member 5, HDGC
- Replacement Item:
- This antibody may replace item sc-135815 from Santa Cruz Biotechnology.
- Description of Target:
- This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.
- Molecular Weight:
- 140 kDa
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Tissue Tool:
- Find tissues and cell lines supported by DNA array analysis to express DSG2.

- RNA Seq:
- Find tissues and cell lines supported by RNA-seq analysis to express DSG2.

- Immunogen:
- Synthesized peptide derived from the Internal region of human Dsg2. Location: 370-450aa.
- Concentration:
- 1 mg/ml
- Specificity:
- Dsg2 Polyclonal Antibody detects endogenous levels of Dsg2 protein.