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- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
Datasheets/Manuals | Printable datasheet for DRAM1 Antibody (OAPB00489) (OAPB00489) |
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Predicted Species Reactivity | Human|Mouse|Rat |
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Product Format | Liquid. DRAM Antibody is supplied in PBS containing 0.02% sodium azide. |
Clonality | Polyclonal |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot |
:: | Buffer: Antibody is supplied in PBS containing 0.02% sodium azide. |
Reconstitution and Storage | DRAM antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Immunogen | Anti-DRAM antibody (4035) was raised against a peptide corresponding to 16 amino acids near the amino terminus of human DRAM. The immunogen is located within amino acids 30-80 of DRAM. |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Human; Mouse; Rat |
Concentration | 1 mg/ml |
Blocking Peptide | For anti-DRAM1 (OAPB00489) antibody is Catalog # OEPB02605 |
Application Info | DRAM antibody can be used for detection of DRAM by Western blot at 0.5 - 1 ug/ml. (Optimal dilution should be determined by user) |
Reference | Crighton D, Wilkinson S, O’Prey J, et al. DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell 2006; 126:121-34.; Gozuacik D and Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene. 2004; 23:2891-906.;Crighton D, Wilkinson S, and Ryan KM. DRAM links autophagy to p53 and programmed cell death. Autophagy 2007; 3:72-4. (07-01D) ; |
Gene Symbol | DRAM1 |
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Gene Full Name | DNA damage regulated autophagy modulator 1 |
Alias Symbols | damage-regulated autophagy modulator;DNA damage-regulated autophagy modulator protein 1;DRAM. |
NCBI Gene Id | 55332 |
Protein Name | Damage-regulated autophagy modulator [Homo sapiens]|DNA damage-regulated autophagy modulator protein 1 |
Description of Target | Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy. |
Uniprot ID | Q8N682 |
Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/AAH18435 |
Nucleotide Accession # | NM_018370.2 |
Molecular Weight | Predicted: 14kD, 26kD Observed: 14 kD, 26kD |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "DRAM1 Antibody (OAPB00489)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".
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How long will it take to receive "DRAM1 Antibody (OAPB00489)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "DRAM1 Antibody (OAPB00489)" provided in?
This item is provided in "Liquid. DRAM Antibody is supplied in PBS containing 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "DRAM1 Antibody (OAPB00489)"?
This target may also be called "damage-regulated autophagy modulator;DNA damage-regulated autophagy modulator protein 1;DRAM." in publications.
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What is the shipping cost for "DRAM1 Antibody (OAPB00489)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "DRAM1 Antibody (OAPB00489)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "DRAM1 Antibody (OAPB00489)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "Predicted: 14kD, 26kD Observed: 14 kD, 26kD".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "DRAM1 Antibody (OAPB00489)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "DRAM1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "DRAM1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "DRAM1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "DRAM1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "DRAM1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "DRAM1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.