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Catalog No: OAPB00489
Size:100UG
Price: $461.00
SKU
OAPB00489
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for DRAM1 Antibody (OAPB00489) (OAPB00489)
Product Info
Predicted Species ReactivityHuman|Mouse|Rat
Product FormatLiquid. DRAM Antibody is supplied in PBS containing 0.02% sodium azide.
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
ApplicationEnzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
::Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and StorageDRAM antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ImmunogenAnti-DRAM antibody (4035) was raised against a peptide corresponding to 16 amino acids near the amino terminus of human DRAM. The immunogen is located within amino acids 30-80 of DRAM.
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceHuman; Mouse; Rat
Concentration1 mg/ml
Blocking PeptideFor anti-DRAM1 (OAPB00489) antibody is Catalog # OEPB02605
Application InfoDRAM antibody can be used for detection of DRAM by Western blot at 0.5 - 1 ug/ml. (Optimal dilution should be determined by user)
ReferenceCrighton D, Wilkinson S, O’Prey J, et al. DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell 2006; 126:121-34.; Gozuacik D and Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene. 2004; 23:2891-906.;Crighton D, Wilkinson S, and Ryan KM. DRAM links autophagy to p53 and programmed cell death. Autophagy 2007; 3:72-4.
(07-01D)
;
Gene SymbolDRAM1
Gene Full NameDNA damage regulated autophagy modulator 1
Alias Symbolsdamage-regulated autophagy modulator;DNA damage-regulated autophagy modulator protein 1;DRAM.
NCBI Gene Id55332
Protein NameDamage-regulated autophagy modulator [Homo sapiens]|DNA damage-regulated autophagy modulator protein 1
Description of TargetLysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy.
Uniprot IDQ8N682
Protein Accession #https://www.ncbi.nlm.nih.gov/protein/AAH18435
Nucleotide Accession #NM_018370.2
Molecular WeightPredicted: 14kD, 26kD Observed: 14 kD, 26kD
  1. What is the species homology for "DRAM1 Antibody (OAPB00489)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".

  2. How long will it take to receive "DRAM1 Antibody (OAPB00489)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "DRAM1 Antibody (OAPB00489)" provided in?

    This item is provided in "Liquid. DRAM Antibody is supplied in PBS containing 0.02% sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "DRAM1 Antibody (OAPB00489)"?

    This target may also be called "damage-regulated autophagy modulator;DNA damage-regulated autophagy modulator protein 1;DRAM." in publications.

  5. What is the shipping cost for "DRAM1 Antibody (OAPB00489)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "DRAM1 Antibody (OAPB00489)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "DRAM1 Antibody (OAPB00489)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "Predicted: 14kD, 26kD Observed: 14 kD, 26kD".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "DRAM1 Antibody (OAPB00489)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "DRAM1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "DRAM1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "DRAM1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "DRAM1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "DRAM1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "DRAM1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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