Catalog No: OPCD02799
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Datasheets/ManualsPrintable datasheet for DR1 Recombinant Protein (OPCD02799)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Ala2-Glu170
::Subcellular Location: Nucleus
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
TagN-terminal His Tag
Gene SymbolDR1
Gene Full Namedown-regulator of transcription 1
Alias SymbolsDown-regulator of transcription 1;NC2;NC2B;NC2-BETA;NCB2;negative cofactor 2;negative cofactor 2-beta;protein Dr1;TATA-binding protein-associated phosphoprotein.
NCBI Gene Id1810
Protein NameProtein Dr1
Description of TargetThe association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Uniprot IDQ01658
Protein Accession #NP_001929.1
Nucleotide Accession #NM_001938.2
Protein Size (# AA)Ala2~Glu170
Molecular Weight24kDa
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