DR1 Recombinant Protein (OPCD02799)

Catalog No: OPCD02799

DR1 Recombinant Protein (OPCD02799) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Ctrl (+), SDS-PAGE, WB
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ala2-Glu170
  Subcellular Location: Nucleus
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: DR1
• Gene Full Name: down-regulator of transcription 1
• Alias Symbols: Down-regulator of transcription 1;NC2;NC2B;NC2-BETA;NCB2;negative cofactor 2;negative cofactor 2-beta;protein Dr1;TATA-binding protein-associated phosphoprotein.
• NCBI Gene Id: 1810
• Protein Name: Protein Dr1
• Description of Target: The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
• Uniprot ID: Q01658
• Protein Accession #: NP_001929.1
• Nucleotide Accession #: NM_001938.2
• Protein Size (# AA): Ala2~Glu170
• Molecular Weight: 24kDa