DR1 Protein (OPPA02418)

Catalog No: OPPA02418 (Formerly GWB-BSP456)

Size:5UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: 0.5mg/ml solution containing 20mM Tris pH-8, 0.1mM PMSF, 0.1M NaCl & 10% glycerol.
• Host: E. Coli
  Product Introduction: DR1 is a phosphoprotein that inhibits both basal and activated levels of transcription. DR1 is phosphorylated in vivo which affects its interaction with TBP. DR1 has a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. By selectively repressing polymerases II and III, DR1 alters the physiological balance of transcriptional output in favor of polymerase I.
  Product Description: DR1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 196 amino acids (1-176 a.a.) and having a molecular mass of 21.6 kDa. The DR1 is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
• Reconstitution and Storage: DR1 Human although stable at 4C for 1 week, should be stored below -18C. Please prevent freeze thaw cycles.
• Purity: Greater than 85.0% as determined by SDS-PAGE.
• Peptide Sequence: MGSSHHHHHH SSGLVPRGSH MASSSGNDDD LTIPRAAINK MIKETLPNVR VANDARELVV NCCTEFIHLI SSEANEICNK SEKKTISPEHVIQALESLGF GSYISEVKEV LQECKTVALK RRKASSRLEN LGIPEEELLR QQQELFAKAR QQQAELAQQE WLQMQQAAQQ AQLAAASASA NQAGSSQDE EDDDDI

Target Info

• Gene Symbol: DR1
• Alias Symbols: NC2, NC2B, NCB2, NC2-BETA
• NCBI Gene Id: 1810
• Protein Name: Protein Dr1
• Description of Target: Recombinant Human Down-Regulator of Transcription 1
• Uniprot ID: Q01658
• Protein Accession #: NP_001929.1
• Protein Size (# AA): Recombinant