Size:100 ul
$229.00
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SKU
ARP38085_T100
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Conjugation Options

ARP38085_T100-FITC Conjugated

ARP38085_T100-HRP Conjugated

ARP38085_T100-Biotin Conjugated

DR1 Antibody - N-terminal region (ARP38085_T100)

Catalog#: ARP38085_T100
Domestic: within 1-2 days delivery International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-133522 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human DR1
Purification Protein A purified
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Complete computational species homology data Anti-DR1 (ARP38085_T100)
Peptide Sequence Synthetic peptide located within the following region: MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLI
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-DR1 (ARP38085_T100) antibody is Catalog # AAP38085 (Previous Catalog # AAPP20259)
Datasheets/Manuals Printable datasheet for anti-DR1 (ARP38085_T100) antibody
Target Reference Gilfillan,S., et al., (2005) J. Biol. Chem. 280 (7), 6222-6230
Publications

Deng, W., Malecová, B., Oelgeschläger, T. & Roberts, S. G. E. TFIIB recognition elements control the TFIIA-NC2 axis in transcriptional regulation. Mol. Cell. Biol. 29, 1389-400 (2009). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish 19114554

Gene Symbol DR1
Official Gene Full Name Down-regulator of transcription 1, TBP-binding (negative cofactor 2)
Alias Symbols NC2, NC2-BETA
NCBI Gene Id 1810
Protein Name Protein Dr1
Description of Target DR1 is a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. DR1 is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. DR1 contains a histone fold motif
Swissprot Id Q01658
Protein Accession # NP_001929
Nucleotide Accession # NM_001938
Protein Size (# AA) 176
Molecular Weight 19kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express DR1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express DR1.
Protein Interactions POLE3; TBP; UBC; BTF3L4; LRSAM1; GOPC; NPLOC4; IPO11; DBNL; ARIH1; TTLL12; ARPC1B; UBE3A; METTL1; HSF1; XPO1; YEATS2; DRAP1; CREB1; CCDC101; TADA2B; SUPT20H; MBIP; WDR5; TADA3; KAT2B; MAP3K7; TADA2A; KAT2A; DR1; ELAVL1; NFYC; NFIL3; TTF2; IRF1;
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