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DR1 antibody - N-terminal region (ARP38085_T100)

100 ul
$229.00
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Conjugation Options

ARP38085_T100-FITC Conjugated

ARP38085_T100-HRP Conjugated

ARP38085_T100-Biotin Conjugated

Gene Symbol:
DR1
NCBI Gene Id:
1810
Official Gene Full Name:
Down-regulator of transcription 1, TBP-binding (negative cofactor 2)
Protein Name:
Protein Dr1
Swissprot Id:
Q01658
Protein Accession #:
NP_001929
Nucleotide Accession #:
NM_001938
Alias Symbols:
NC2, NC2-BETA
Replacement Item:
This antibody may replace item sc-133522 from Santa Cruz Biotechnology.
Description of Target:
DR1 is a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. DR1 is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. DR1 contains a histone fold motif
Protein Size (# AA):
176
Molecular Weight:
19kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Protein A purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express DR1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express DR1.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human DR1
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Complete computational species homology data:
Anti-DR1 (ARP38085_T100)
Peptide Sequence:
Synthetic peptide located within the following region: MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLI
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
POLE3; TBP; UBC; BTF3L4; LRSAM1; GOPC; NPLOC4; IPO11; DBNL; ARIH1; TTLL12; ARPC1B; UBE3A; METTL1; HSF1; XPO1; YEATS2; DRAP1; CREB1; CCDC101; TADA2B; SUPT20H; MBIP; WDR5; TADA3; KAT2B; MAP3K7; TADA2A; KAT2A; DR1; ELAVL1; NFYC; NFIL3; TTF2; IRF1;
Blocking Peptide:
For anti-DR1 (ARP38085_T100) antibody is Catalog # AAP38085 (Previous Catalog # AAPP20259)
Datasheets/Manuals:
Printable datasheet for anti-DR1 (ARP38085_T100) antibody
Target Reference:
Gilfillan,S., et al., (2005) J. Biol. Chem. 280 (7), 6222-6230
Publications:

Deng, W., Malecová, B., Oelgeschläger, T. & Roberts, S. G. E. TFIIB recognition elements control the TFIIA-NC2 axis in transcriptional regulation. Mol. Cell. Biol. 29, 1389-400 (2009). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish 19114554

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