DPP4 Human - Human Dipeptidyl-Peptidase 4 Protein (OPPA01797)

Catalog No: OPPA01797 (Formerly GWB-BSP166)

Size:2ng

Product Info

• Product Format: Each 70ng were lyophilized from 29.1ul containing 2mM Tris-HCl, pH 8.0. Physical appearance: Filtered lyophilized (freeze-dried) powder.
• Host: Human Placenta
• Additional Information: Solubility: Add deionized water to prepare a working stock solution of approximately 0.5mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile
  Biological Activity: One unit is defined as the amount of enzyme which will hydrolyze 1um of H-Gly-Pro-pNA per 1min at 25C, pH 7.8.
  Specific Activity: 13U/mg.
  Product Introduction: Group IB secretory phospholipase A2 (sPLA2-IB) mediates cell proliferation, cell migration, hormone release and eicosanoid production via its receptor in peripheral tissues. In the CNS, high-affinity binding sites of sPLA2-IB have been documented. sPLA2-IB induced neuronal cell death in a concentrationdependent manner depending on PGD2 metabolites, especially Delta12-PGJ2 that might mediate sPLA2-IB-induced apoptosis. The secretory PLA2 (sPLA2) family, in which 10 isozymes have been identified, consists of lowmolecular weight, Ca2+-requiring secretory enzymes that have been implicated in a number of biological processes, such as modification of eicosanoid generation, inflammation, and host defense.
• Reconstitution and Storage: Store lyophilized protein at -20C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4C for a limited period of time; it does not show any change after two weeks at 4C. The lyophilized protein remains stable until the expiry date when stored at -20C.
• Purity: Greater than 95% as determined by SDS-PAGE.
• Specificity: The protein was prepared from tissue shown to be non-reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1and 2by FDA required tests. This product is intended for research useonly.

Target Info

• Gene Symbol: DPP4
• Alias Symbols: CD26, ADABP, ADCP2, DPPIV, TP103
• NCBI Gene Id: 1803
• Protein Name: Dipeptidyl peptidase 4
• Description of Target: Human Dipeptidyl-Peptidase 4
• Uniprot ID: P27487
• Protein Accession #: NP_001926.2