DPP10 Antibody - middle region (OAAB05596)

Catalog No: OAAB05596

Size:400ul

Western blot analysis of DPP10 Antibody (Center) in Y79, MDA-MB231 cell line and mouse liver, brain tissue lysates (35ug/lane). DPP10 (arrow) was detected using the purified Pab.

DPP10 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DPP10 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid. PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: WB, IHC-P, ELISA
  Cellular Location: Cell membrane, Single-pass II membrane protein
  Tissue Location: Found in serum, T-cells and brain (at protein level). Expressed in brain, pancreas, spinal cord and adrenal glands.
• Reconstitution and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This DPP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-177 amino acids from the Central region of human DPP10.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: 0.5 mg/ml
• Application Info: WB: 1:1000
  IHC-P: 1:50~100
• Publications:

  Manipulation of dipeptidylpeptidase 10 in mouse and human in vivo and in vitro models indicates a protective role in asthma. Dis Model Mech. 11, (2018). 29361513

Target Info

• Gene Symbol: DPP10
• Alias Symbols: DPL2, DPPY, DPRP3, DPRP-3
• NCBI Gene Id: 57628
• Protein Name: Inactive dipeptidyl peptidase 10
• Description of Target: DPP10 is a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties.
• Uniprot ID: Q8N608
• Protein Accession #: NP_001004360.2
• Molecular Weight: 91 kDa