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DPF3 Antibody - middle region (ARP34293_P050)

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100 ul
$319.00
In Stock
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Conjugation Options

ARP34293_P050-FITC Conjugated

ARP34293_P050-HRP Conjugated

ARP34293_P050-Biotin Conjugated

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Gene Symbol:
DPF3
Official Gene Full Name:
D4, zinc and double PHD fingers, family 3
NCBI Gene Id:
8110
Protein Name:
Zinc finger protein DPF3
Swissprot Id:
Q92784
Protein Accession #:
NP_036206
Nucleotide Accession #:
NM_012074
Alias Symbols:
CERD4, FLJ14079
Description of Target:
DPF3 is a muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). DPF3 specifically binds acetylated lysines on histone 3 and 4 (H3K14ac, H3K9ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac). In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. It thereby probably plays an essential role in heart and skeletal muscle development.
Protein Size (# AA):
357
Molecular Weight:
40kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express DPF3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express DPF3.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human DPF3
Predicted Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Complete computational species homology data:
Anti-DPF3 (ARP34293_P050)
Peptide Sequence:
Synthetic peptide located within the following region: KDGFTSESTTLEALLRGEGVEKKVDAREEESIQEIQRVLENDENVEEGNE
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
SMARCA4; SMARCA2; RELA; NFKB1; SMARCD1; SMARCC1; SMARCB1; ESRRA;
Blocking Peptide:
For anti-DPF3 (ARP34293_P050) antibody is Catalog # AAP34293 (Previous Catalog # AAPP05643)
Datasheets/Manuals:
Printable datasheet for anti-DPF3 (ARP34293_P050) antibody
Sample Type Confirmation:

DPF3 is supported by BioGPS gene expression data to be expressed in NCIH226

Target Reference:
Hoyal,C.R., (er) J Carcinog 4, 13 (2005)
Publications:

Theodorou, M. et al. Identification of a STAT5 target gene, Dpf3, provides novel insights in chronic lymphocytic leukemia. PLoS One 8, e76155 (2013). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 24155890

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