DPEP1 Antibody - N-terminal region (OAAB15178)

Catalog No: OAAB15178

Size:400ul

DPEP1 Antibody (N-term) (Cat. # OAAB15178) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the DPEP1 antibody detected the DPEP1 protein (arrow).

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB
• Additional Information: Cellular Location: Apical cell membrane; Lipid-anchor, GPI- anchor. Cell projection, microvillus membrane; Lipid-anchor, GPI- anchor. Note=Brush border membrane.
• Reconstitution and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This DPEP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DPEP1.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: 0.48 mg/ml
• Intended Use: For research use only.
• Application Info: WB: 1:1000

Target Info

• Gene Symbol: DPEP1
• Alias Symbols: MDP, RDP, MBD1
• NCBI Gene Id: 1800
• Protein Name: Dipeptidase 1
• Description of Target: DPEP1 (EC 3.4.13.11) is a kidney membrane enzyme that hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates, e.g., leukotriene D4. DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics, such as penem and carbapenem. Earlier, beta-lactamase enzymes were thought to occur only in bacteria, where their probable function was in protecting the organisms against the action of beta-lactam antibiotics. These antibiotics exhibit selective toxicity against bacteria but virtual inertness against many eukaryotic cells.
• Uniprot ID: P16444
• Protein Accession #: NP_001121613.1
• Molecular Weight: 46 kDa