DOK2 Antibody (Phospho-Tyr345) (OASG02216)

Catalog No: OASG02216

Size:100 uL

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human Dok-2 around the phosphorylation site of Y345. Location: 290-370aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Phospho-Tyr345
• Specificity: Phospho-Dok-2 (Tyr345) Polyclonal Antibody detects endogenous levels of Dok-2 protein only when phosphorylated at Y345.
• Application Info: IHC 1:100-1:300; ELISA 1:20000;

Target Info

• Gene Symbol: DOK2
• Gene Full Name: docking protein 2, 56kDa
• Alias Symbols: p56DOK, p56dok-2
• NCBI Gene Id: 9046; 13449;
• Description of Target: The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.
• Uniprot ID: O60496, O70469
• Molecular Weight: 46/54 kDa