DOCK2 Recombinant Protein (OPCD02779)

Catalog No: OPCD02779

DOCK2 Recombinant Protein (OPCD02779) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Conjugation: Unconjugated
• Application: Ctrl (+), SDS-PAGE, WB
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Isoelectric Point: 9.2
  Residues: Ile390-Glu635
  Subcellular Location: Membrane. Cytoplasm
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 97%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: DOCK2
• Gene Full Name: dedicator of cytokinesis 2
• Alias Symbols: dedicator of cyto-kinesis 2;dedicator of cytokinesis protein 2;IMD40.
• NCBI Gene Id: 1794
• Protein Name: Dedicator of cytokinesis protein 2
• Description of Target: Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.
• Uniprot ID: Q92608
• Protein Accession #: NP_004937.1
• Nucleotide Accession #: NM_004946.2
• Protein Size (# AA): Ile390~Glu635
• Molecular Weight: 32kDa