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Datasheets/Manuals | Printable datasheet for anti-DNM1L (ARP52329_P050) antibody |
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Tested Species Reactivity | Human, Mouse | ||||||
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Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish | ||||||
Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. | ||||||
Clonality | Polyclonal | ||||||
Host | Rabbit | ||||||
Application | IHC, WB | ||||||
Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. | ||||||
Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human DNM1L | ||||||
Purification | Affinity Purified | ||||||
Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 85%; Zebrafish: 93% | ||||||
Peptide Sequence | Synthetic peptide located within the following region: IRQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVG | ||||||
Concentration | 0.5 mg/ml | ||||||
Blocking Peptide | For anti-DNM1L (ARP52329_P050) antibody is Catalog # AAP52329 (Previous Catalog # AAPP42835) | ||||||
Sample Type Confirmation | DNM1L is supported by BioGPS gene expression data to be expressed in HeLa | ||||||
Enhanced Validation |
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Publications | Su, Y. C., Chiu, H. W., Hung, J. C. & Hong, J. R. Beta-nodavirus B2 protein induces hydrogen peroxide production, leading to Drp1-recruited mitochondrial fragmentation and cell death via mitochondrial targeting. Apoptosis 19, 1457-70 (2014). 25008790 |
Gene Symbol | DNM1L |
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Gene Full Name | Dynamin 1-like |
Alias Symbols | DLP1, DRP1, DVLP, EMPF, OPA5, EMPF1, DYMPLE, HDYNIV |
NCBI Gene Id | 10059 |
Protein Name | Dynamin-1-like protein |
Description of Target | The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated. |
Uniprot ID | O00429 |
Protein Accession # | NP_036192 |
Nucleotide Accession # | NM_012062 |
Protein Size (# AA) | 736 |
Molecular Weight | 82 kDa |
Protein Interactions | ZBTB24; UBC; SCG3; SH3GL1; RRM2; MAGEA3; MAGEA1; MARCH5; EGFR; VPS26A; SSB; CARS; ATP6V1C1; APEH; PSMG3; FAM129B; TBC1D15; CYHR1; ARFIP1; JMJD6; SEC24A; SOX2; DNM1L; MIEF2; MFF; PEX14; LRRK2; MIEF1; COPS5; GABRR1; MUL1; SUMO2; PARK2; PEX25; PEX11G; PEX11A |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "DNM1L Antibody - N-terminal region (ARP52329_P050)"?
The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish".
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How long will it take to receive "DNM1L Antibody - N-terminal region (ARP52329_P050)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
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What buffer format is "DNM1L Antibody - N-terminal region (ARP52329_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "DNM1L Antibody - N-terminal region (ARP52329_P050)"?
This target may also be called "DLP1, DRP1, DVLP, EMPF, OPA5, EMPF1, DYMPLE, HDYNIV" in publications.
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What is the shipping cost for "DNM1L Antibody - N-terminal region (ARP52329_P050)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "DNM1L Antibody - N-terminal region (ARP52329_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "DNM1L Antibody - N-terminal region (ARP52329_P050)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "82 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "DNM1L Antibody - N-terminal region (ARP52329_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "DNM1L"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "DNM1L"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "DNM1L"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "DNM1L"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "DNM1L"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "DNM1L"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.