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DNAK Antibody (OASE00439)

  • Catalog#: OASE00439
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200ul
$370.00
Discontinued
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Conjugation Options

OASE00439-FITC Conjugated

OASE00439-HRP Conjugated

OASE00439-Biotin Conjugated

NCBI Gene Id:
5729354
Swissprot Id:
A8JIK8
Protein Accession #:
XP_001703815.1
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Rabbit antiserum
Application:
WB
Immunogen:
Recombinant DNAK of Chlamydomonoas reinhardtii
Reconstitution and Storage:
Store at -20C. Shipping in Blue Ice or 4C.
Datasheets/Manuals:
Printable datasheet for OASE00439
Dilution:
1:5000 (WB)
Additional Information:
Background Info: Detects ~70kDa.
:::
Scientific Background: The prokaryotic Hsp70 protein family includes DNA K, HSCA (Hsc66), and HscC (Hsc62) (1). DNAK interacts with DNAJ and GrpE heat shock protein chaperones to fold substrate proteins in an ATP-driven cycle (2). These proteins are also involved in cell protection from environmental stress and other functions which are vital for a living cell. And like eukaryotic Hsp70 homologs, DNAK participates in the assembly/disassembly of protein complexes (3, 4).
Target Reference:
1. Gohre et al. (2006) The Plant Cell. 18: 1454-1466. 2. Zylicz M., et al. (1983) PNAS USA. 80: 6431-6435.
3. Hightower L. (1980) J Cell Physiol. 102: 407-427.
4. Pelham H.B.R. (1986) Cell. 46: 959-961.
Storage Buffer:
Lyophilized rabbit antiserum

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