DNAJB1 Recombinant Protein (OPCD04003)

Catalog No: OPCD04003

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Met1-Ile340
  Isoelectric Point: 8.8
  Subcellular Location: Nucleus, Cytoplasm
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: DNAJB1
• Gene Full Name: DnaJ heat shock protein family (Hsp40) member B1
• Alias Symbols: DnaJ (Hsp40) homolog, subfamily B, member 1;dnaJ homolog subfamily B member 1;dnaJ protein homolog 1;Hdj1;heat shock 40 kDa protein 1;Hsp40;HSPF1;human DnaJ protein 1;radial spoke 16 homolog B;RSPH16B;Sis1.
• NCBI Gene Id: 3337
• Protein Name: DnaJ homolog subfamily B member 1
• Description of Target: Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response (PubMed:9499401). Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro) (PubMed:24318877).
• Uniprot ID: P25685
• Protein Accession #: NP_001287843.1
• Nucleotide Accession #: NM_001300914.1
• Protein Size (# AA): Met1~Ile340
• Molecular Weight: 39kDa