Size:200 ul
$329.00
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SKU
OAAB21125
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More Information
Predicted Species Reactivity Human, Mouse
Product Format Liquid
Clonality Polyclonal
Clone RB54010
Isotype Rabbit Ig
Host Rabbit
Application WB
Additional Information Function: Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-28941 from Santa Cruz Biotechnology.
Immunogen This DLG4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 548-579 amino acids from human DLG4.
Purification Protein A column purification, followed by peptide affinity purification
Predicted Homology Based on Immunogen Sequence Human, Mouse
Concentration 500 ug/mL
Datasheets/Manuals Printable datasheet for anti-DLG4 (OAAB21125) antibody
Preservative 0.09% Sodium Azide
Formulation Purified polyclonal antibody, supplied in PBS with 0.09% sodium azide.
Application Info WB: 1:2000
Target Reference Stathakis D.G.,et al.Genomics 44:71-82(1997).
Stathakis D.G.,et al.Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases.
Stathakis D.G.,et al.J. Neurochem. 73:2250-2265(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Gene Symbol DLG4
Official Gene Full Name discs large homolog 4
Alias Symbols PSD95, SAP90, SAP-90
NCBI Gene Id 1742
Description of Target This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
Swissprot Id P78352
Protein Accession # NP_001122299.1
Nucleotide Accession # NM_001128827.1
Molecular Weight 80 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express DLG4.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express DLG4.
  1. What is the species homology for "DLG4 Antibody (OAAB21125)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".

  2. How long will it take to receive "DLG4 Antibody (OAAB21125)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "DLG4 Antibody (OAAB21125)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "DLG4 Antibody (OAAB21125)"?

    This target may also be called "PSD95, SAP90, SAP-90" in publications.

  5. What is the shipping cost for "DLG4 Antibody (OAAB21125)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "DLG4 Antibody (OAAB21125)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "DLG4 Antibody (OAAB21125)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "80 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "DLG4 Antibody (OAAB21125)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "DLG4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "DLG4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "DLG4"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "DLG4"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "DLG4"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "DLG4"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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