DLD Recombinant Protein (OPCD02758)

Catalog No: OPCD02758

DLD Recombinant Protein (OPCD02758) using SDS-PAGE

DLD Recombinant Protein (OPCD02758) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Thr45-Lys271
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His and GST Tag

Target Info

• Gene Symbol: Dld
• Gene Full Name: dihydrolipoamide dehydrogenase
• Alias Symbols: branched chain alpha-keto acid dehydrogenase complex subunit E3;Dihydrolipoamide dehydrogenase;dihydrolipoyl dehydrogenase, mitochondrial.
• NCBI Gene Id: 13382
• Protein Name: Dihydrolipoyl dehydrogenase, mitochondrial
• Description of Target: Lipoamide dehydrogenase is a component of the glycine cleavage system as well as an E3 component of three alpha-ketoacid dehydrogenase complexes (pyruvate-, alpha-ketoglutarate-, and branched-chain amino acid-dehydrogenase complex) (By similarity). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion (By similarity). A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A (By similarity). In monomeric form may have additional moonlighting function as serine protease (PubMed:17404228). Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction (By similarity).
• Uniprot ID: O08749
• Protein Accession #: NP_031887.2
• Nucleotide Accession #: NM_007861.5
• Protein Size (# AA): Thr45~Lys271
• Molecular Weight: 54.01kDa