DGAT1 Recombinant Protein (OPCD02722)

Catalog No: OPCD02722

DGAT1 Recombinant Protein (OPCD02722) using SDS-PAGE

DGAT1 Recombinant Protein (OPCD02722) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ala180-Arg427
  Subcellular Location: Endoplasmic reticulum lumen
  Isoelectric Point: 10.0
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 100 ug/mL (prior to lyoph)
• Purity: > 97%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: DGAT1
• Gene Full Name: diacylglycerol O-acyltransferase 1
• Alias Symbols: ACAT related gene product 1;ACAT-related gene product 1;acyl coenzyme A:cholesterol acyltransferase related gene 1;acyl-CoA retinol O-fatty-acyltransferase;acyl-CoA:diacylglycerol acyltransferase;ARAT;ARGP1;DGAT;diacylglycerol O-acyltransferase 1;DIAR7;diglyceride acyltransferase.
• NCBI Gene Id: 8694
• Protein Name: Diacylglycerol O-acyltransferase 1
• Description of Target: Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.
• Uniprot ID: O75907
• Protein Accession #: NP_036211.2
• Nucleotide Accession #: NM_012079.5
• Protein Size (# AA): Ala180~Arg427
• Molecular Weight: 27kDa