DEGS2 Antibody - C-terminal region (OAAB00599)

Catalog No: OAAB00599

Size:400ul

DEGS2 Antibody (C-term) western blot analysis in Hela cell lysates (35ug/lane).This demonstrates the DEGS2 antibody detected the DEGS2 protein (arrow).

DEGS2 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DEGS2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Product Info

• Predicted Species Reactivity: Human, Mouse, Cow
• Product Format: Liquid PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: WB, IHC-P, ELISA
• Additional Information: Cellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein.
  Tissue Location: Highly expressed in skin, intestine, and kidney.
• Reconstitution and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This DEGS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-290 amino acids from the C-terminal region of human DEGS2.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: 0.5 mg/ml
• Application Info: WB: 1:1000
  IHC-P: 1:50~100

Target Info

• Gene Symbol: DEGS2
• Alias Symbols: DES2, FADS8, C14orf66
• NCBI Gene Id: 123099
• Protein Name: Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2
• Description of Target: DEGS2 encodes a bifunctional enzyme that is involved in the biosynthesis of phytosphingolipids in human skin and in other phytosphingolipid-containing tissues. This enzyme can act as a sphingolipid delta(4)-desaturase, and also as a sphingolipid C4-hydroxylase.
• Uniprot ID: Q6QHC5
• Protein Accession #: NP_996801.2
• Molecular Weight: 37 kDa