Size:100 ul
$229.00
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ARP36375_T100
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Conjugation Options

ARP36375_T100-FITC Conjugated

ARP36375_T100-HRP Conjugated

ARP36375_T100-Biotin Conjugated

DDX21 Antibody - C-terminal region (ARP36375_T100)

Catalog#: ARP36375_T100
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Guinea Pig, Horse, Human, Pig, Rabbit, Rat
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-104860 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human DDX21
Purification Protein A purified
Predicted Homology Based on Immunogen Sequence Cow: 86%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Pig: 93%; Rabbit: 93%; Rat: 93%
Complete computational species homology data Anti-DDX21 (ARP36375_T100)
Peptide Sequence Synthetic peptide located within the following region: FRGQRDGNRRFRGQREGSRGPRGQRSGGGNKSNRSQNKGQKRSFSKAFGQ
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-DDX21 (ARP36375_T100) antibody is Catalog # AAP36375 (Previous Catalog # AAPP08433)
Datasheets/Manuals Printable datasheet for anti-DDX21 (ARP36375_T100) antibody
Sample Type Confirmation

DDX21 is supported by BioGPS gene expression data to be expressed in HepG2

Target Reference Henning,D., et al., (2003) J. Biol. Chem. 278 (52), 52307-52314
Publications

Miyazawa, N. et al. Human cell growth regulator Ly-1 antibody reactive homologue accelerates processing of preribosomal RNA. Genes Cells 19, 273-86 (2014). WB, Cow, Dog, Guinea Pig, Horse, Human, Pig, Rabbit, Rat 24495227

Romanova, L. et al. Critical role of nucleostemin in pre-rRNA processing. J. Biol. Chem. 284, 4968-77 (2009). WB, Cow, Dog, Guinea Pig, Horse, Human, Pig, Rabbit, Rat 19106111

Gene Symbol DDX21
Official Gene Full Name DEAD (Asp-Glu-Ala-Asp) box helicase 21
Alias Symbols GUA, GURDB, RH-II/GU, RH-II/GuA
NCBI Gene Id 9188
Protein Name Nucleolar RNA helicase 2
Description of Target DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX21 encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.
Swissprot Id Q9NR30
Protein Accession # NP_004719
Nucleotide Accession # NM_004728
Protein Size (# AA) 783
Molecular Weight 86kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express DDX21.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express DDX21.
Protein Interactions HUWE1; PA2G4; KPNA3; CEP250; SUMO2; SUMO3; STAU1; IVNS1ABP; UBC; MDM2; LGR4; SUMO1; ERG; WWOX; EED; rev; SRPK2; SRPK3; FBXO6; TARDBP; LYN; AICDA; PAN2; vif; WHSC1; VCAM1; ITGA4; IL7R; FN1; CSNK2A1; YWHAE; SMURF1; H2AFX; APTX; ESR1; FTSJ3; PCDHA2; RRP7A; R
  1. What is the species homology for "DDX21 Antibody - C-terminal region (ARP36375_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Cow, Dog, Guinea Pig, Horse, Human, Pig, Rabbit, Rat".

  2. How long will it take to receive "DDX21 Antibody - C-terminal region (ARP36375_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "DDX21 Antibody - C-terminal region (ARP36375_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "DDX21 Antibody - C-terminal region (ARP36375_T100)"?

    This target may also be called "GUA, GURDB, RH-II/GU, RH-II/GuA" in publications.

  5. What is the shipping cost for "DDX21 Antibody - C-terminal region (ARP36375_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "DDX21 Antibody - C-terminal region (ARP36375_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "DDX21 Antibody - C-terminal region (ARP36375_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "86kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "DDX21 Antibody - C-terminal region (ARP36375_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "DDX21"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "DDX21"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "DDX21"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "DDX21"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "DDX21"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "DDX21"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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