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Datasheets/Manuals | Printable datasheet for DDIT4L Antibody (OAEE01029) (OAEE01029) |
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Predicted Species Reactivity | Human |
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Product Format | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
Clonality | Monoclonal |
Clone | DDIT-03 |
Isotype | IgG1 |
Host | Mouse |
Conjugation | R-PE |
Application | Flow cytometry |
Reconstitution and Storage | 2°C to 8°C |
Immunogen | N-terminal recombinant fragment of human DDIT4L (amino acids 2-98) |
Purification | Purified by size-exclusion chromatography |
Concentration | 0.1 mg/ml |
Specificity | The mouse monoclonal antibody DDIT-03 recognizes DDIT4L / REDD2 protein, which belongs to stress-induced proteins involved in mediation of cell death. |
Formulation | PE |
Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent. |
Reference | Cuaz-Pérolin C, Furman C, Larigauderie G, Legedz L, Lasselin C, Copin C, Jaye M, Searfoss G, Yu KT, Duverger N, Nègre-Salvayre A, Fruchart JC, Rouis M.REDD2 gene is upregulated by modified LDL or hypoxia and mediates human macrophage cell death. Arterioscler Thromb Vasc Biol. 2004 Oct;24(10):1830-5. Corradetti MN, Inoki K, Guan KL: The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway. J Biol Chem. 2005 Mar 18;280(11):9769-72. Imen JS, Billiet L, Cuaz-Pérolin C, Michaud N, Rouis M: The regulated in development and DNA damage response 2 (REDD2) gene mediates human monocyte cell death through a reduction in thioredoxin-1 expression. Free Radic Biol Med. 2009 May 15;46(10):1404-10 |
Gene Symbol | DDIT4L |
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Gene Full Name | DNA damage inducible transcript 4 like |
Alias Symbols | DNA damage-inducible transcript 4-like protein;HIF-1 responsive protein RTP801-like;homolog of mouse SMHS1;protein regulated in development and DNA damage response 2;REDD2;REDD-2;regulated in development and DNA damage response 2;Rtp801L. |
NCBI Gene Id | 115265 |
Protein Name | DNA damage-inducible transcript 4-like protein |
Description of Target | Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. |
Uniprot ID | Q96D03 |
Protein Accession # | NP_660287.1; XP_005262778.1 |
Nucleotide Accession # | NM_145244.3; XM_005262721.1 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "DDIT4L Antibody (OAEE01029)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "DDIT4L Antibody (OAEE01029)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "DDIT4L Antibody (OAEE01029)" provided in?
This item is provided in "Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "DDIT4L Antibody (OAEE01029)"?
This target may also be called "DNA damage-inducible transcript 4-like protein;HIF-1 responsive protein RTP801-like;homolog of mouse SMHS1;protein regulated in development and DNA damage response 2;REDD2;REDD-2;regulated in development and DNA damage response 2;Rtp801L." in publications.
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What is the shipping cost for "DDIT4L Antibody (OAEE01029)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "DDIT4L Antibody (OAEE01029)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "DDIT4L Antibody (OAEE01029)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "DDIT4L Antibody (OAEE01029)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "DDIT4L"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "DDIT4L"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "DDIT4L"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "DDIT4L"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "DDIT4L"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "DDIT4L"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.