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DCTN2 Antibody - N-terminal region : HRP (ARP58450_P050-HRP)
Datasheets/Manuals | Printable datasheet for anti-DCTN2 (ARP58450_P050-HRP) antibody |
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Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
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Product Format | Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
Clonality | Polyclonal |
Host | Rabbit |
Conjugation | HRP: Horseradish Peroxidase |
Application | WB |
Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human DCTN2 |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
Peptide Sequence | Synthetic peptide located within the following region: ADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAFAQELEELTSTSVEHI |
Concentration | 0.5 mg/ml |
Blocking Peptide | For anti-DCTN2 (ARP58450_P050-HRP) antibody is Catalog # AAP58450 (Previous Catalog # AAPP34559) |
Subunit | 2 |
Reference | Camargo,L.M., (2007) Mol. Psychiatry 12 (1), 74-86 |
Gene Symbol | DCTN2 |
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Gene Full Name | Dynactin 2 (p50) |
Alias Symbols | RBP50, DCTN50, HEL-S-77, DYNAMITIN |
NCBI Gene Id | 10540 |
Protein Name | Dynactin subunit 2 |
Description of Target | DCTN2 is a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Uniprot ID | Q13561 |
Protein Accession # | NP_006391 |
Nucleotide Accession # | NM_006400 |
Protein Size (# AA) | 406 |
Molecular Weight | 45kDa |
Protein Interactions | KIFC3; CCDC172; HAUS1; BLOC1S6; DCTN2; BICD2; DYNC1I1; DCTN1; UBC; FLNB; NUP43; LEO1; SEH1L; ACTR10; DCTN4; DCTN3; ACTR1A; ACTR1B; RABEP1; LMNB1; GADD45A; KPNA2; SMURF1; DYNLRB1; STRN4; RANBP9; TPM4; SNRPA1; PSMD4; PSMD1; PSMC4; PSMC2; POLR2D; POLR2A; MCM |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "DCTN2 Antibody - N-terminal region : HRP (ARP58450_P050-HRP)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".
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How long will it take to receive "DCTN2 Antibody - N-terminal region : HRP (ARP58450_P050-HRP)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
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What buffer format is "DCTN2 Antibody - N-terminal region : HRP (ARP58450_P050-HRP)" provided in?
This item is provided in "Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "DCTN2 Antibody - N-terminal region : HRP (ARP58450_P050-HRP)"?
This target may also be called "RBP50, DCTN50, HEL-S-77, DYNAMITIN" in publications.
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What is the shipping cost for "DCTN2 Antibody - N-terminal region : HRP (ARP58450_P050-HRP)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "DCTN2 Antibody - N-terminal region : HRP (ARP58450_P050-HRP)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "DCTN2 Antibody - N-terminal region : HRP (ARP58450_P050-HRP)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "45kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "DCTN2 Antibody - N-terminal region : HRP (ARP58450_P050-HRP)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "DCTN2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "DCTN2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "DCTN2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "DCTN2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "DCTN2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "DCTN2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.