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DAXX Antibody - N-terminal region : FITC (ARP60159_P050-FITC)

100 ul
$289.00
In Stock
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Conjugation Options

ARP60159_P050 Unconjugated

ARP60159_P050-HRP Conjugated

ARP60159_P050-Biotin Conjugated

Gene Symbol:
DAXX
NCBI Gene Id:
1616
Swissprot Id:
Q9UER7
Protein Accession #:
NP_001341
Alias Symbols:
Name=DAXX,
Replacement Item:
This antibody may replace item sc-51586 from Santa Cruz Biotechnology.
Description of Target:
This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
Protein Size (# AA):
740
Molecular Weight:
81kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express DAXX.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express DAXX.
Immunogen:
The immunogen is a synthetic peptide directed towards the N-terminal region of Human DAXX
Predicted Species Reactivity:
Human
Peptide Sequence:
Synthetic peptide located within the following region: KLNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQSPRTRGSRRQIQRL
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution and Storage:
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Concentration:
0.5 mg/ml
Protein Interactions:
FAM9B; SSX2IP; SUMO1; UBE2I; UBC; GOLGA2; CARD9; PBXIP1; CDCA7L; NECAB2; RASSF1; PML; MDM2; H3F3A; DNMT1; TP53; ATRX; CARM1; PRMT1; WHSC1L1; CUL3; SPOP; HIPK2; PDCD4; DNMT3A; USP7; UBB; RELB; DAXX; CREB1; CBS; ATM; HIST1H4F; HIST1H3C; TRAF3; HIST4H4; BTBD
Blocking Peptide:
For anti-DAXX (ARP60159_P050-FITC) antibody is Catalog # AAP60159
Datasheets/Manuals:
Printable datasheet for anti-DAXX (ARP60159_P050-FITC) antibody
Conjugation:
FITC (FAM): Excitation 495 nm/ Emission 520 nm

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