DAB1 Antibody (OAGA06200)

Catalog No: OAGA06200

Size:100 ul

Sample (50 ug of whole cell lysate)
A: mouse brain
7.5% SDS PAGE
diluted at 1:3000

DAB1 antibody [N1N3] detects DAB1 protein at cytosol on mouse duodenum by immunohistochemical analysis.
Sample: Paraffin-embedded mouse duodenum.
DAB1 antibody [N1N3] dilution: 1:500.

DAB1 antibody [N1N3] detects DAB1 protein at mitochondria by immunofluorescent analysis.
Sample: HepG2 cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: DAB1 protein stained by DAB1 antibody [N1N3] diluted at 1:500.
Blue: Hoechst 33342 staining.

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: ICC, IF, IHC-P, WB
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human Dab1. The exact sequence is proprietary.
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 1 mg/ml
• Preservative: 0.01% Thimerosal
• Application Info: Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 1:100-1:1000, WB: 1:1000-1:10000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: DAB1
• Gene Full Name: DAB1, reelin adaptor protein
• Alias Symbols: SCA37
• NCBI Gene Id: 1600
• Protein Name: disabled homolog 1
• Description of Target: The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain.
• Uniprot ID: O75553
• Protein Accession #: NP_066566.3
• Nucleotide Accession #: NM_021080.3