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Catalog No: OPCD02615
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OPCD02615
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Datasheets/ManualsPrintable datasheet for CYP2D6 Recombinant Protein (OPCD02615)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Leu236-Gln472
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 90%
SourceE.coli
TagN-terminal His Tag
Gene SymbolCYP2D6
Gene Full Namecytochrome P450 family 2 subfamily D member 6
Alias Symbolscholesterol 25-hydroxylase;CPD6;CYP2D;CYP2D7AP;CYP2D7BP;CYP2D7P2;CYP2D8P2;CYP2DL1;CYPIID6;cytochrome P450 2D6;cytochrome P450, family 2, subfamily D, polypeptide 6;cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2;cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2;cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2;cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2;cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6;cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1;cytochrome P450-DB1;debrisoquine 4-hydroxylase;flavoprotein-linked monooxygenase;microsomal monooxygenase;nonfunctional cytochrome P450 2D6;P450C2D;P450DB1;P450-DB1;xenobiotic monooxygenase.
NCBI Gene Id1565
Protein NameCytochrome P450 2D6
Description of TargetResponsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.
Uniprot IDP10635
Protein Accession #NP_000097.3
Nucleotide Accession #NM_000106.5
Protein Size (# AA)Leu236~Gln472
Molecular Weight27kDa
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