CXCR6 Antibody - C-terminal region (OABB01237)

Catalog No: OABB01237

Size:100UG

Anti- CXCR6 antibody, OABB01236-1, Western blotting
All lanes: Anti CXCR6 (OABB01236-1) at 0.5ug/ml
Lane 1: Rat Brain Tissue Lysate at 50ug
Lane 2: Rat Testis Tissue Lysate at 50ug
Lane 3: Rat Spleen Tissue Lysate at 50ug
Lane 4: Mouse Brain Tissue Lysate at 50ug
Lane 5: Mouse Testis Tissue Lysate at 50ug
Predicted bind size: 39 kDa
Observed bind size: 39 kDa

Anti- CXCR6 antibody, OABB01236-1, IHC(P)
IHC(P): Rat Spleen Tissue

Product Info

• Tested Species Reactivity: Mouse, Rat
• Predicted Species Reactivity: Hamster|Mouse|Rat
• Product Format: Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Clonality: Polyclonal
• Clone: Polyclonal
• Isotype: Rabbit IgG
• Host: Rabbit
• Application: Immunohistochemistry|Western blot
• Additional Information: Notes: Tested Species: In-house tested species with positive results.
  Predicted Species: Species predicted to be fit for the product based on sequence similarities.
  By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections.
  Other applications have not been tested.
  Optimal dilutions should be determined by end users.
  
  Background: CXCR6(Chemokine,CXC Motif, Receptor 6), also known as STRL33, is a protein that in humans is encoded by the CXCR6 gene. By Southern blot analysis of genomic DNA and somatic cell hybrid analysis, Liao et al.(1997) mapped the single-copy STRL33 gene to chromosome 3. Matloubian et al.(2000) found that human and mouse cells expressing CXCR6 showed a strong chemotactic response to CXCL16 but not to other chemokines. The authors concluded that CXCL16 and CXCR6 probably function in interactions between dendritic cells and T cells and in regulating T-cell migration in the splenic red pulp. Kim et al.(2001) concluded that CXCR6 may be important in the trafficking of effector T cells mediating type-1 inflammation.
• Reconstitution and Storage: 2°C to 8°C|-20°C
• Immunogen: Polypeptide
• Purification: Affinity Purified
• Concentration: 500 ug/ml
• Specificity: No cross reactivity with other proteins.
• Application Info: Western blot: 0.1-0.5 ug/ml: Mouse, Rat
  Immunohistochemistry (Paraffin-embedded Section): 0.5-1 ug/ml: Rat: Mouse: By Heat
• Storage Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Description: Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 6(CXCR6) detection. Tested with WB, IHC-P in Mouse;Rat.

Target Info

• Gene Symbol: Cxcr6
• Gene Full Name: chemokine (C-X-C motif) receptor 6
• Alias Symbols: BB217514;BO;BONZO;C-X-C chemokine receptor type 6;CXCR-6;CXC-R6;STR;STRL33.
• NCBI Gene Id: 80901
• Protein Name: C-X-C chemokine receptor type 6
• Description of Target: Receptor for the C-X-C chemokine CXCL16.
• Uniprot ID: Q9EQ16
• Molecular Weight: 40468 MW