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| Datasheets/Manuals | Printable datasheet for CXCR4 Antibody - N-terminal region (OASA06080) |
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| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid. Phosphate buffered saline |
| Clonality | Polyclonal |
| Isotype | Polyclonal IgG |
| Host | Goat |
| Application | Enzyme-linked immunosorbent assay|Immunohistochemistry-Paraffin|Western blot |
| Additional Information | Histology Positive Control Tissue: Spleen |
| :: | Preservative Stabilisers: 0.1% Sodium Azide (NaN3) 0.1% Bovine Serum Albumin Antiserum Preparation: Antiserum to human CD184 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography. |
| :: | Approx Protein Conc: IgG concentration 1.0mg/ml Buffer Solutions: Phosphate buffered saline |
| Reconstitution and Storage | -20°C |
| Immunogen | Synthetic peptide TEEMGSGDYDSMKEPCFREENANFNKC corresponding to amino acids 17-43 within the N-terminal region of human CD184 / CXCR4. |
| Predicted Homology Based on Immunogen Sequence | Human |
| Concentration | 1 mg/ml |
| Specificity | OASA06080 recognises an epitope within the N-terminal (NT) region of human CD184, otherwise known as CXCR4 (C-X-C chemokine receptor type 4), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, ubiquitously expressed in blood and tissue cells, which acts as a specific receptor for the chemokine SDF-1 (Stromal cell-derived factor 1). Interaction of CD184 with SDF-1 mediates the chemotaxis of progenitor and mature blood cells, and is critical for B- lymphopoiesis and myelopoiesis. CD184 is a major co-receptor for infection by T-cell tropic strains of HIV1, and also a primary receptor for some HIV2 isolates. OASA06080 is reported as suitable for use in immunofluorescence studies. |
| Application Info | Immunohistology - Paraffin: 1/150 ELISA: 1/25000 Western Blotting: 1/250 |
| Application Data | Application #1: Paraffin embedded human spleen stained with Goat anti Human CD184 (N-terminal) -  |
| Gene Symbol | CXCR4 |
|---|---|
| Alias Symbols | FB22, HM89, LAP3, LCR1, NPYR, WHIM, CD184, LAP-3, LESTR, NPY3R, NPYRL, WHIMS, HSY3RR, NPYY3R, D2S201E |
| NCBI Gene Id | 7852 |
| Protein Name | C-X-C chemokine receptor type 4 |
| Description of Target | GOAT ANTI HUMAN CD184 (N-TERMINAL) |
| Uniprot ID | P61073 |
| Protein Accession # | NP_001008540.1 |
| Protein Size (# AA) | 356 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "CXCR4 Antibody - N-terminal region (OASA06080)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "CXCR4 Antibody - N-terminal region (OASA06080)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "CXCR4 Antibody - N-terminal region (OASA06080)" provided in?
This item is provided in "Liquid. Phosphate buffered saline".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "CXCR4 Antibody - N-terminal region (OASA06080)"?
This target may also be called "FB22, HM89, LAP3, LCR1, NPYR, WHIM, CD184, LAP-3, LESTR, NPY3R, NPYRL, WHIMS, HSY3RR, NPYY3R, D2S201E" in publications.
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What is the shipping cost for "CXCR4 Antibody - N-terminal region (OASA06080)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "CXCR4 Antibody - N-terminal region (OASA06080)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "CXCR4 Antibody - N-terminal region (OASA06080)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "CXCR4 Antibody - N-terminal region (OASA06080)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "CXCR4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "CXCR4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "CXCR4"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "CXCR4"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "CXCR4"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "CXCR4"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
