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Catalog No: ARP30799_P050
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ARP30799_P050
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CXCR4 Antibody - N-terminal region (ARP30799_P050)

Datasheets/ManualsPrintable datasheet for anti-CXCR4 (ARP30799_P050) antibody
Product Info
Tested Species ReactivityHuman, Mouse
Predicted Species ReactivityHuman, Mouse, Horse, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationFC, IHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human CXCR4
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceHorse: 89%; Human: 91%; Mouse: 77%; Pig: 91%; Rabbit: 85%; Rat: 77%
Peptide SequenceSynthetic peptide located within the following region: MEGISIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFL
Concentration0.5 mg/ml
Blocking PeptideFor anti-CXCR4 (ARP30799_P050) antibody is Catalog # AAP30799 (Previous Catalog # AAPS08210)
ReferenceYoshitake,N., (2008) Br. J. Cancer 98 (10), 1682-1689
Publications

Biopolymer-delivered vascular endothelial growth factor improves renal outcomes following revascularization. Am J Physiol Renal Physiol. 316, F1016-F1025 (2019). 30892933

Description
Gene SymbolCXCR4
Gene Full NameChemokine (C-X-C motif) receptor 4
Alias SymbolsFB22, HM89, LAP3, LCR1, NPYR, WHIM, CD184, LAP-3, LESTR, NPY3R, NPYRL, WHIMS, HSY3RR, NPYY3R, D2S201E
NCBI Gene Id7852
Protein NameC-X-C chemokine receptor type 4
Description of TargetCXCR4 is a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Uniprot IDP61073
Protein Accession #NP_003458
Nucleotide Accession #NM_003467
Protein Size (# AA)352
Molecular Weight40 kDa
Protein InteractionsUBC; ITCH; nef; P4HB; CD4; env; MYBL2; ST13; ATP13A2; CXCL12; PTPN11; STAM; CAV1; SUMO4; HLA-C; SDC4; HSPA8; GNA13; STAT5B; SOCS3; SOCS1; CCR5; PTK2; STAT2; STAT1; JAK3; DPP4; PTPN6; VAV1; CXCR4; MYH9; PTPRC; JAK2; JAK1; GNAI1; ELANE; CTSG; ADRBK2; ARRB2;
  1. What is the species homology for "CXCR4 Antibody - N-terminal region (ARP30799_P050)"?

    The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Human, Mouse, Horse, Pig, Rabbit".

  2. How long will it take to receive "CXCR4 Antibody - N-terminal region (ARP30799_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "CXCR4 Antibody - N-terminal region (ARP30799_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CXCR4 Antibody - N-terminal region (ARP30799_P050)"?

    This target may also be called "FB22, HM89, LAP3, LCR1, NPYR, WHIM, CD184, LAP-3, LESTR, NPY3R, NPYRL, WHIMS, HSY3RR, NPYY3R, D2S201E" in publications.

  5. What is the shipping cost for "CXCR4 Antibody - N-terminal region (ARP30799_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CXCR4 Antibody - N-terminal region (ARP30799_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CXCR4 Antibody - N-terminal region (ARP30799_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "40 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CXCR4 Antibody - N-terminal region (ARP30799_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CXCR4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CXCR4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CXCR4"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CXCR4"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CXCR4"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CXCR4"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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