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Catalog No: OAAJ01740
Size:100 ul
Price: $319.00
SKU
OAAJ01740
Availability: Domestic: within 2-3 week delivery | International: 2-3 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for anti-CUL2 (OAAJ01740) antibody
Product Info
Predicted Species ReactivityHuman, Mouse
Product FormatLiquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
ClonalityPolyclonal
HostRabbit
ApplicationWB, IHC, IF, ICC
Reconstitution and StorageStore at -20C. Stable for 12 months from date of receipt.
ImmunogenA synthesized peptide derived from human Cullin 2
PurificationAffinity-chromatography
Concentration1 mg/ml
SpecificityCullin 2 antibody detects endogenous levels of total Cullin 2
Application InfoWB: 1:500~1:3000 IHC: 1:50~1:200 IF/ICC: 1:100~1:500
Gene SymbolCUL2
Gene Full Namecullin 2
Alias SymbolsCUL-2, CUL2, cullin 2, Cullin-2, MGC131970
NCBI Gene Id8453
Description of TargetCUL2 Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1. The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF).
Uniprot IDQ13617
Molecular Weight82 kDa, 84 kDa
  1. What is the species homology for "CUL2 Antibody (OAAJ01740)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".

  2. How long will it take to receive "CUL2 Antibody (OAAJ01740)"?

    This item is available "Domestic: within 2-3 week delivery | International: 2-3 weeks".

  3. What buffer format is "CUL2 Antibody (OAAJ01740)" provided in?

    This item is provided in "Liquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CUL2 Antibody (OAAJ01740)"?

    This target may also be called "CUL-2, CUL2, cullin 2, Cullin-2, MGC131970" in publications.

  5. What is the shipping cost for "CUL2 Antibody (OAAJ01740)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CUL2 Antibody (OAAJ01740)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CUL2 Antibody (OAAJ01740)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "82 kDa, 84 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CUL2 Antibody (OAAJ01740)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CUL2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CUL2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CUL2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CUL2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CUL2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CUL2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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