CTH Recombinant Protein (OPCD02452)

Catalog No: OPCD02452

CTH Recombinant Protein (OPCD02452) using SDS-PAGE

CTH Recombinant Protein (OPCD02452) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Thr163-Asp382
  Subcellular Location: Cytoplasm
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 90%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: CTH
• Gene Full Name: cystathionine gamma-lyase
• Alias Symbols: CSE;cystathionase (cystathionine gamma-lyase);cystathionine gamma-lyase;cysteine desulfhydrase;cysteine-protein sulfhydrase;gamma-cystathionase;homoserine deaminase;homoserine dehydratase.
• NCBI Gene Id: 1491
• Protein Name: Cystathionine gamma-lyase
• Description of Target: Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function.
• Uniprot ID: P32929
• Protein Accession #: NP_001177392.1
• Nucleotide Accession #: NM_001190463.1
• Protein Size (# AA): Thr163~Asp382
• Molecular Weight: 26kDa