Catalog No: OPCD02451
Price: $0.00
SKU
OPCD02451
Availability: Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery
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Datasheets/Manuals | Printable datasheet for CTH Recombinant Protein (OPCD02451) |
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Predicted Species Reactivity | Mouse|Mus musculus |
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Product Format | Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
Host | E.coli |
Conjugation | Unconjugated |
Application | Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot |
Additional Information | Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) |
:: | Residues: Phe14-Val224 |
:: | Subcellular Location: Cytoplasm |
Reconstitution and Storage | 2°C to 8°C|-80°C |
Concentration | 200 ug/mL (prior to lyoph) |
Purity | > 97% |
Source | E.coli |
Tag | N-terminal His Tag |
Gene Symbol | Cth |
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Gene Full Name | cystathionase (cystathionine gamma-lyase) |
Alias Symbols | 0610010I13Rik;AI314617;BC019483;CS;CSE;Cys3;cystathionine gamma-lyase;cysteine-protein sulfhydrase;Gamma-cystathionase. |
NCBI Gene Id | 107869 |
Protein Name | Cystathionine gamma-lyase |
Description of Target | Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function. |
Uniprot ID | Q8VCN5 |
Protein Accession # | NP_666065.1 |
Nucleotide Accession # | NM_145953.2 |
Protein Size (# AA) | Phe14~Val224 |
Molecular Weight | 27kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
-
See our General FAQ page.
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