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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
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| Datasheets/Manuals | Printable datasheet for CTCFL Antibody (OACA06868) (OACA06868) |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | Enzyme-linked immunosorbent assay|Immunohistochemistry |
| Reconstitution and Storage | -20°C or -80°C |
| Immunogen | Recombinant Human Transcriptional repressor CTCFL protein (1-270AA) |
| Purification | Affinity Purified |
| Preservative | 0.02% sodium azide |
| Formulation | PBS with, 50% glycerol, pH7.3. |
| Reference | [1]"BAT3 and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expression."Nguyen P., Bar-Sela G., Sun L., Bisht K.S., Cui H., Kohn E., Feinberg A.P., Gius D.Mol. Cell. Biol. 28:6720-6729(2008). [2]"The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer."Klenova E.M., Morse H.C. III, Ohlsson R., Lobanenkov V.V.Semin. Cancer Biol. 12:399-414(2002). [3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."The MGC Project TeamGenome Res. 14:2121-2127(2004). |
| Gene Symbol | CTCFL |
|---|---|
| Gene Full Name | CCCTC-binding factor like |
| Alias Symbols | BORIS;BORIS-like protein;brother of the regulator of imprinted sites;cancer/testis antigen 27;CCCTC-binding factor;CT27;CTCF paralog;CTCF-like protein;CTCF-T;dJ579F20.2;HMGB1L1;transcriptional repressor CTCFL;Zinc finger protein CTCF-T. |
| NCBI Gene Id | 140690 |
| Protein Name | Transcriptional repressor CTCFL |
| Description of Target | Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases at these sites (By similarity). Seems to act as tumor suppressor. In association with DNMT1 and DNMT3B, involved in activation of BAG1 gene expression by binding to its promoter. Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters. |
| Uniprot ID | Q8NI51 |
| Protein Accession # | NP_001255969 |
| Nucleotide Accession # | NM_001269040 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "CTCFL Antibody (OACA06868)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "CTCFL Antibody (OACA06868)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
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What buffer format is "CTCFL Antibody (OACA06868)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "CTCFL Antibody (OACA06868)"?
This target may also be called "BORIS;BORIS-like protein;brother of the regulator of imprinted sites;cancer/testis antigen 27;CCCTC-binding factor;CT27;CTCF paralog;CTCF-like protein;CTCF-T;dJ579F20.2;HMGB1L1;transcriptional repressor CTCFL;Zinc finger protein CTCF-T." in publications.
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What is the shipping cost for "CTCFL Antibody (OACA06868)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "CTCFL Antibody (OACA06868)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "CTCFL Antibody (OACA06868)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "CTCFL Antibody (OACA06868)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "CTCFL"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "CTCFL"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "CTCFL"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "CTCFL"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "CTCFL"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "CTCFL"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
