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CSTB cDNA (ANA10366)

1ug
$189.00
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Gene Symbol:
CSTB
NCBI Gene Id:
1476
Description of Target:
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).
Nucleotide Accession #:
BC010532
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CSTB.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CSTB.
Tag:
None
Protein Interactions:
UBC; SARNP; DPP7; BAG3; CFTR; ECT2; SEC24A; NUDC; MAT2A; FLNB; DCUN1D1; CUL3; RAD21; SPRY2; CTSL; CTSD; CTSH; CTSB; CST3; VHL;
Reconstitution and Storage:
Centrifuge the vials after receiving and add 5 μl ddH2O
Datasheets/Manuals:
Printable datasheet for anti-CSTB (ANA10366) antibody

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