CSNK2B Protein (OPPA01123)

Catalog No: OPPA01123 (Formerly GWB-4B6793)

Size:3UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: CSNK2B lyophilized from 25mM Tris-HCl, 500mM NaCl, 1mM DTT, 1mM EDTA, protease inhibitor cocktail, pH 8.5. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
• Host: E. Coli
• Additional Information: Solubility: Solubilize in distilled H2O or 50% glycerol.
  Biological Activity: Specific activity > 1U/mg.
  Unit Definition: 1U = 1 umol/min at 37C) using the synthetic peptide RRRDDDSDDD.
  Product Introduction: The Casein kinase 2 (EC2.7.11.1) is a serine/threonine-selective protein kinasethat is a tetramer of two alpha subunits and two beta subunits. The alpha subunits have the catalytic kinase domain. Casein kinase 2 has been implicated in cell cyclecontrol, DNA repair, regulation of the circadian rhythmand other cellular processes.Casein kinase 2 activity has been reported to be activated following Wnt signaling pathwayactivation. A Pertussis toxin-sensitive G proteinand Disheveled appear to be an intermediary between Wnt-mediated activation of the Frizzled receptor and activation of casein kinase 2.Mice that lack casein kinase 2 alpha prime have a defect in the morphology of developing sperm.
  Product Description: Casein Kinase 2 beta Human Recombinant is a non-glycosylated polypeptide having a molecular mass of 24.9 kDa. Casein Kinase 2 is purified by proprietary chromatographic techniques.
• Reconstitution and Storage: Lyophilized CSNK2B although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution CSNK2B should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please avoid freeze-thaw cycles.
• Purity: Greater than 95% as determined by SDS-PAGE.

Target Info

• Gene Symbol: CK2b Active
• Alias Symbols: G5A, CK2B, CK2N, Ckb1, Ckb2, CSK2B, POBINDS
• NCBI Gene Id: 1460
• Protein Name: Casein kinase II subunit beta
• Description of Target: Recombinant Human Casein Kinase 2 beta Active
• Uniprot ID: P67870
• Protein Accession #: NP_001311.3
• Protein Size (# AA): Recombinant