CSNK1E Antibody (OAAF02280)

Catalog No: OAAF02280 (Formerly GWB-ASD528)

Size:100 ug

Western blot analysis of extracts from LOVO cells, using CKI-epsilon Antibody. The lane on the right is treated with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using CKI-epsilon Antibody. The picture on the right is treated with the synthesized peptide.

Immunofluorescence analysis of HeLa cells, using CKI-epsilon Antibody. The picture on the right is treated with the synthesized peptide.

Product Info

• Predicted Species Reactivity: Human|Mouse
• Product Format: Liquid
• Clonality: Polyclonal
• Host: Rabbit
• Application: Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
• Reconstitution and Storage: -20°C
• Immunogen: The antiserum was produced against synthesized peptide derived from human CKI-epsilon.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Specificity: CKI-ε antibody detects endogenous levels of total CKI-ε protein.
• Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Dilution: The optimal working dilution should be determined by the end user.
• Application Info: WB: 1:500~1:3000; IHC: 1:50~1:100; IF: 1:100~1:500; ELISA: 1:20000
• Reference: Fish K.J., J. Biol. Chem. 270:14875-14883(1995).
  Okamura A., Blood 103:2997-3004(2004).
  Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).

Target Info

• Gene Symbol: CSNK1E|TPTEP2-CSNK1E
• Gene Full Name: casein kinase 1 epsilon|TPTEP2-CSNK1E readthrough
• Alias Symbols: casein kinase I isoform epsilon;CKIe;CKIepsilon;CKI-epsilon;HCKIE;LOC400927-CSNK1E;LOC400927-CSNK1E readthrough.
• NCBI Gene Id: 102800317|1454
• Protein Name: Casein kinase I isoform epsilon
• Description of Target: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1 and DVL2. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation.
• Uniprot ID: P49674
• Protein Accession #: NP_001885.1
• Molecular Weight: 47 kDa