CSNK1A1 Antibody (OAAF02545)

Catalog No: OAAF02545 (Formerly GWB-ASD765)

Size:100 ug

Immunohistochemistry analysis of paraffin-embedded human testis tissue, using CKI-alpha1/L Antibody. The picture on the right is treated with the synthesized peptide.

Immunofluorescence analysis of A549 cells, using CKI-alpha1/L Antibody. The picture on the right is treated with the synthesized peptide.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid
• Clonality: Polyclonal
• Host: Rabbit
• Application: Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
• Reconstitution and Storage: -20°C
• Immunogen: The antiserum was produced against synthesized peptide derived from human CKI-alpha1/L.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Specificity: CKI-α1/L antibody detects endogenous levels of total CKI-α1/L protein.
• Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Dilution: The optimal working dilution should be determined by the end user.
• Application Info: IHC: 1:50~1:100; IF: 1:100~1:500; ELISA: 1:20000
• Reference: The MGC Project Team, Genome Res. 14:2121-2127(2004).
  Sjoeblom T., Science 314:268-274(2006).

Target Info

• Gene Symbol: CSNK1A1|CSNK1A1L
• Gene Full Name: casein kinase 1 alpha 1|casein kinase 1 alpha 1 like
• Alias Symbols: casein kinase I alpha S-like;casein kinase I isoform alpha;casein kinase I isoform alpha-like;CK1;CK1a;CKIa;CKI-alpha;CKI-alpha-like;clock regulator kinase;down-regulated in lung cancer;epididymis secretory sperm binding protein Li 77p;HEL-S-77p;HLCDGP1;PRO2975.
• NCBI Gene Id: 122011|1452
• Protein Name: Casein kinase I isoform alpha|Casein kinase I isoform alpha-like
• Description of Target: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity).|Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis (PubMed:11955436, PubMed:1409656, PubMed:18305108). May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed:23902688).
• Uniprot ID: P48729|Q8N752
• Protein Accession #: NP_001020276.1
• Molecular Weight: 39 kDa