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Catalog No: OPCD05195
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OPCD05195
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Datasheets/ManualsPrintable datasheet for CSF1 Recombinant Protein (OPCD05195)
Product Info
Predicted Species ReactivityMouse|Mus musculus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Lys33-Ser204
::Subcellular Location: Cell membrane; Single-pass type I membrane protein. Secreted, extracellular spac
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 90%
SourceE.coli
TagN-terminal His Tag
Gene SymbolCsf1
Gene Full Namecolony stimulating factor 1 (macrophage)
Alias SymbolsC87615;Csf;CSF-;Csfm;macrophage colony-stimulating factor 1;M-CS;MCSF;op;osteopetrosis.
NCBI Gene Id12977
Protein NameMacrophage colony-stimulating factor 1
Description of TargetCytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.
Uniprot IDP07141
Protein Accession #NP_001107001.1
Nucleotide Accession #NM_001113529.1
Protein Size (# AA)Lys33~Ser204
Molecular Weight24kDa
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