CSE1L Antibody (OAGA08483)

Catalog No: OAGA08483

Size:100 ul

CSE1L antibody [GT729] detects CSE1L protein by western blot analysis.
A. 30 ug 293T whole cell lysate/extract
B. 30 ug A431 whole cell lysate/extract
C. 30 ug HeLa whole cell lysate/extract
D. 30 ug HepG2 whole cell lysate/extract
7.5 % SDS-PAGE
CSE1L antibody [GT729] dilution: 1:1000

CSE1L antibody [GT729] detects CSE1L protein by western blot analysis.
A. 30 ug Neuro2A whole cell lysate/extract
B. 30 ug GL261 whole cell lysate/extract
C. 30 ug C8D30 whole cell lysate/extract
D. 30 ug NIH-3T3 whole cell lysate/extrac
E. 30 ug BCL-1 whole cell lysate/extrac
F. 30 ug Raw 264.7 whole cell lysate/extract
G. 30 ug C2Cl2 whole cell lysate/extract
7.5 % SDS-PAGE
CSE1L antibody [GT729] dilution: 1:1000

CSE1L antibody [GT729] detects CSE1L protein by western blot analysis.
A. 30 ug PC-12 whole cell lysate/extract
B. 30 ug Rat2 whole cell lysate/extract
7.5 % SDS-PAGE
CSE1L antibody [GT729] dilution: 1:1000

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid
• Clonality: Monoclonal
• Clone: GT729
• Isotype: IgG2a
• Host: Mouse
• Application: WB
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human CSE1L. The exact sequence is proprietary.
• Purification: Affinity purified by Protein G.
• Concentration: 1 mg/ml
• Application Info: Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: PBS

Target Info

• Gene Symbol: CSE1L
• Gene Full Name: chromosome segregation 1 like
• Alias Symbols: CAS, CSE1, XPO2
• NCBI Gene Id: 1434
• Protein Name: exportin-2
• Description of Target: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene.
• Uniprot ID: P55060
• Protein Accession #: NP_001243064.1
• Nucleotide Accession #: NM_001256135.1