CRYAB Protein (OPPA01063)

Catalog No: OPPA01063 (Formerly GWB-CD3E51)

Size:20UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: The CRYAB protein (1mg/ml) solution contains 20mM Tris-HCl buffer pH-7.5, 50mM NaCl and 1mM EDTA. Physical appearance: Sterile filtered colorless solution.
• Host: E. Coli
  Product Introduction: Alpha crystallins are composed of two gene products ; alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20). They act as molecular chaperones and hold them in in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional function of a-crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-B is expressed widely in many tissues and organs and occurs in many neurological diseases.
  Product Description: Recombinant CRYAB produced in E.Coli is a single,non-glycosylated polypeptide chain containing 175amino acids and having a molecular mass of 20,159 Dalton. CRYAB is purified by proprietary chromatographic techniques.
• Reconstitution and Storage: Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Avoid multiple freeze-thaw cycles.
• Purity: Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
• Peptide Sequence: MDIAIHHPWI RRPFFPFHSP SRLFDQFFGE HLLESDLFPT STSLSPFYLR PPSFLRAPSWFDTGLSEMRL EKDRFSVNLD VKHFSPEELK VKVLGDVIEV HGKHEERQDE HGFISREFHRKYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVT AAPKK.

Target Info

• Gene Symbol: CRYAB
• Alias Symbols: MFM2, CRYA2, CTPP2, HSPB5, CMD1II, CTRCT16, HEL-S-101
• NCBI Gene Id: 1410
• Protein Name: Alpha-crystallin B chain
• Description of Target: Recombinant Human Crystallin Alpha B
• Uniprot ID: P02511
• Protein Accession #: NP_001876.1
• Protein Size (# AA): Recombinant