Crem Antibody - C-terminal region (ARP34778_P050)

Catalog No: ARP34778_P050

Host: Mouse
Target Name: CREB1
Sample Tissue: Mouse Kidney
Antibody Dilution: 1ug/ml

25 ug of the indicated Mouse whole cell extracts was loaded onto a 10-20% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. Recommended dilution for antibody is 1-3 ug/mL. Multiple isoforms of this protein are expressed in various mouse tissues, and at least two isoforms (~36 kDa and ~24 kDa) are detected in this experiment.

Product Info

• Tested Species Reactivity: Mouse, Rat
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Rat Crem
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%
• Peptide Sequence: Synthetic peptide located within the following region: KNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKAE
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-Crem (ARP34778_P050) antibody is Catalog # AAP34778
• Enhanced Validation:

  Relative Expression (Western Blot)

• Description:
  View product citations for Crem Antibody - C-terminal region (ARP34778_P050) on CiteAb

Target Info

• Gene Symbol: Crem
• Alias Symbols: Icer
• NCBI Gene Id: 25620
• Protein Name: cAMP-responsive element modulator
• Description of Target: Crem is a transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform Delta is an activator. Crem plays a role in spermatogenesis and is involved in spermatid maturation. Binding of isoform Tau (activator) to CRE is increased by CREB3L4. The CREM isoform Tau-CREB3L4 heterodimer functions through CRE and may recruit HIRA to CRE to regulate histone exchange.
• Uniprot ID: Q03061
• Protein Accession #: NP_001104330
• Nucleotide Accession #: NM_001110860
• Protein Size (# AA): 345
• Molecular Weight: 37 kDa
• Protein Interactions: Stub1; Ubc;