CREBBP Antibody (OAAJ02255)

Catalog No: OAAJ02255

Size:100 ul

Western blot analysis on HeLa cell lysate using CBP Antibody

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB, IHC, IF, ICC
• Reconstitution and Storage: Store at -20C. Stable for 12 months from date of receipt.
• Immunogen: A synthesized peptide derived from human CBP
• Purification: Immunogen affinity purified
• Concentration: 1 mg/ml
• Specificity: CBP antibody detects endogenous levels of CBP
• Application Info: WB: 1:500-1:2000 IHC: 1:50-1:200 IF/ICC: 1:100-1:500

Target Info

• Gene Symbol: CREBBP
• Gene Full Name: CREB binding protein
• Alias Symbols: CBP, RSTS, KAT3A, MKHK1, RSTS1
• NCBI Gene Id: 1387
• Description of Target: CBP a protein acetyltransferase that can transcriptionally activate histones. Acetylates the NCOA3 coactivator. Binds specifically to phosphorylated CREB1 and enhances its transcriptional activity toward cAMP-responsive genes. Methylation of the KIX domain by CARM1 blocks association with CREB, blocking CREB signaling, and activating the apoptotic response. Found in a complex containing NCOA2, NCOA3, IKKA, IKKB, and IKBKG. Probably part of a complex with HIF1A and EP300. Interacts with the C-terminal region of CITED4. The TAZ-type 1 domain interacts with HIF1A. Interacts with MAF, SRCAP, CARM1, ELF3, MLLT7/FOXO4, N4BP2, NCOA1, NCOA3, NCOA6, PCAF, PELP1, PML, SMAD1, SMAD2, SMAD3, SPIB and TRERF1. Interacts with HTLV-1 Tax, p30II, and HIV-1 Tat. Interacts with KLF1;
• Uniprot ID: Q92793
• Molecular Weight: 265 kDa