Catalog No: OPPA02088 (Formerly GWB-1A0505)
Size:5UG
Price: $75.00
SKU
OPPA02088
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
Bulk
Order
Aviva's
Satisfaction
Guarantee
Contact Us:
Shipping Info:
  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.

CRABP1 Protein (OPPA02088)

Datasheets/ManualsPrintable datasheet for OPPA02088
Product Info
Predicted Species ReactivityHuman
Product FormatThe CRABP1 protein solution contains 20mM Tris-HCl buffer (pH8.0) and 10% glycerol. Physical appearance: Sterile Filtered colorless solution.
HostE. Coli
::Product Introduction: CRABP1 is a member of special carrier proteins for members of the vitamin A family. It is believed that CRABP1 has an essential role in retinoic acid-mediated differentiation and proliferation processes. Though, CRABP1 is structurally similar to the cellular retinol-binding proteins, it binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue. CRABP1 is constitutively expressed and is thought to have different functions in the cell than the related CRABP2. CRABP1 forms a beta-barrel structure which accommodates hydrophobic ligands in its interior.Loss of CRABP1 function as a result of hypermethylation of its promoter leads to pathogenesis of papillary thyroid carcinoma. Furthermore, frequent methylation-associated silencing of CRABP1 is linked to esophageal squamous-cell carcinoma.
Product Description: CRABP1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 137 amino acids and having a molecular mass of 15.5kDa. The CRABP1 is purified by proprietary chromatographic techniques.
Reconstitution and StorageCRABP1 although stable 4C for 4 weeks, should be stored desiccated below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles.
PurityGreater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Peptide SequenceMPNFAGTWKM RSSENFDELL KALGVNAMLR KVAVAAASKP HVEIRQDGDQ FYIKTSTTVR TTEINFKVGE GFEEETVDGR KCRSLATWEN ENKIHCTQTL LEGDGPKTYW TRELANDELI LTFGADDVVC TRIYVRE.
Gene SymbolCRABP1
Alias SymbolsRBP5, CRABP, CRABPI, CRABP-I
NCBI Gene Id1381
Protein NameCellular retinoic acid-binding protein 1
Description of TargetRecombinant Human Cellular Retinoic Acid Binding Protein 1
Uniprot IDP29762
Protein Accession #NP_004369.1
Protein Size (# AA)Recombinant
Write Your Own Review
You're reviewing:CRABP1 Protein (OPPA02088)
Your Rating
We found other products you might like!