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CR1 Antibody (OASA01919)

0.2 mg
$459.00
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Gene Symbol:
CR1
NCBI Gene Id:
1378
Protein Name:
Complement receptor type 1
Swissprot Id:
P17927
Protein Accession #:
NP_000564.2
Alias Symbols:
KN, C3BR, C4BR, CD35, CR1
Replacement Item:
This antibody may replace item sc-166329 from Santa Cruz Biotechnology.
Description of Target:
MOUSE ANTI HUMAN CD35
Protein Size (# AA):
2039
Host:
Mouse
Clonality:
Monoclonal
Application:
IHC-AFF, FC, IHC-FFPE, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CR1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CR1.
Immunogen:
The immunogen for anti-CR1 antibody: human acute monocytic leukaemia cells
Predicted Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Human
Product Format:
Purified IgG - liquid
Reconstitution and Storage:
Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Datasheets/Manuals:
Printable datasheet for anti-CR1 antibody - OASA01919
Specificity:
CD35
Clone:
E11
Isotype:
IgG1
Application Info:
Flow Cytometry:    1/50 - 1/200
Immunohistology - Frozen:    1ug/ml - 10ug/ml
Immunohistology - Paraffin(1):    1ug/ml - 10ug/ml
(1) Special conditions apply. - See [*].
Application Data:
Application #1: Staining of human peripheral blood monocytes with Mouse anti Human CD35
Application #2: Staining of human peripheral blood granulocytes with Mouse anti Human CD35:RPE
Application #3: Staining of human peripheral blood lymphocytes with Mouse anti Human CD35
Additional Information:
Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
Histology Positive Control Tissue: Human Tonsil
:::
Preparation: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Preservative Stabilisers: 0.09% - Sodium Azide
:::
Approx Protein Conc: IgG concentration 1 mg/ml
Buffer Solutions: Phosphate buffered saline pH7.4
Target Reference:
1. Hogg, N. et al. (1984) Identification of an anti-monocyte monoclonal antibody that is specific for membrane complement receptor type one (CR1). Eur. J. Immunol. 14: 236-243.
2. Yoshino, N. et al. (2000) Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of Cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. Exp. Anim.49 (2): 97-110
3. Birmingham, D. J. et al. (1996) The baboon erythrocyte complement receptor is a glycophosphatidylinositol-linked protein encoded by a homologue of the human CR1-like genetic element J. Immunol. 157: 2586 - 2592.
4. Sopper, S. et al. (1997) Lymphocyte subsets and expression of differentiation markers in blood and lymphoid organs of Rhesus monkeys. Cytometry 29: 351-362.

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