Catalog No: OAAB08599
Size:400ul
Price: $438.00
SKU
OAAB08599
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
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  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for OAAB08599
Product Info
Predicted Species ReactivityHuman, Mouse
Product FormatLiquid. PBS with 0.09% (W/V) sodium azide.
ClonalityPolyclonal
IsotypeIg
HostRabbit
ApplicationWB, IHC-P
::Function: May be a regulatory subunit of cytochrome c oxidase that mediates the higher level of energy production in target cells by estrogen.
Cellular Location: Mitochondrion inner membrane (By similarity).
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis COX7A2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the Central region of human COX7A2L.
PurificationThis antibody is purified through a protein A column, followed by peptide affinity purification.
Predicted Homology Based on Immunogen SequenceHuman; Mouse
ConcentrationApproximately 0.5mg/ml. Actual concentration varies with each lot.
Sample Type Confirmation

COX7A2L is strongly supported by BioGPS gene expression data to be expressed in A549

Application InfoWB: 1:1000
IHC-P: 1:10~50
Gene SymbolCOX7A2L
Alias SymbolsEB1, SCAF1, SCAFI, SIG81, COX7AR, COX7RP
NCBI Gene Id9167
Protein NameCytochrome c oxidase subunit 7A-related protein, mitochondrial
Description of TargetCytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen.
Uniprot IDO14548
Protein Accession #NP_004709.2
Molecular Weight12615 Da
  1. What is the species homology for "COX7A2L Antibody - middle region (OAAB08599)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".

  2. How long will it take to receive "COX7A2L Antibody - middle region (OAAB08599)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "COX7A2L Antibody - middle region (OAAB08599)" provided in?

    This item is provided in "Liquid. PBS with 0.09% (W/V) sodium azide. ".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "COX7A2L Antibody - middle region (OAAB08599)"?

    This target may also be called "EB1, SCAF1, SCAFI, SIG81, COX7AR, COX7RP" in publications.

  5. What is the shipping cost for "COX7A2L Antibody - middle region (OAAB08599)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "COX7A2L Antibody - middle region (OAAB08599)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "COX7A2L Antibody - middle region (OAAB08599)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "12615 Da".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "COX7A2L Antibody - middle region (OAAB08599)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "COX7A2L"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "COX7A2L"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "COX7A2L"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "COX7A2L"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "COX7A2L"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "COX7A2L"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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