CORO1A Antibody - C-terminal region (ARP38900_T100)

Catalog No: ARP38900_T100

WB Suggested Anti-CORO1A Antibody Titration: 1.25ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysateCORO1A is supported by BioGPS gene expression data to be expressed in Jurkat

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CORO1A
• Purification: Protein A purified
• Predicted Homology Based on Immunogen Sequence: Cow: 93%; Dog: 93%; Horse: 100%; Human: 100%; Mouse: 77%; Pig: 90%; Rabbit: 79%; Rat: 83%
• Peptide Sequence: Synthetic peptide located within the following region: ELRVNRGLDTGRRRAAPEASGTPSSDAVSRLEEEMRKLQATVQELQKRLD
• Concentration: 1.0 mg/ml
• Blocking Peptide: For anti-CORO1A (ARP38900_T100) antibody is Catalog # AAP38900 (Previous Catalog # AAPY00709)
• Sample Type Confirmation:

  CORO1A is supported by BioGPS gene expression data to be expressed in Jurkat

• Reference: Anand,P.K. (2005) FEMS Microbiol. Lett. 250 (1), 137-144

Target Info

• Gene Symbol: CORO1A
• Gene Full Name: Coronin, actin binding protein, 1A
• Alias Symbols: p57, IMD8, TACO, CLABP, HCORO1, CLIPINA
• NCBI Gene Id: 11151
• Protein Name: Coronin-1A
• Description of Target: CORO1A is a novel actin-binding protein with a WD repeat and a leucine zipper motif. CORO1A forms homodimers, that the association is mediated by the leucine zipper structure in the C-terminal region, and that it plays a role in the cross-linking of F-actin in the cell. The leukocyte plasma membrane associates with the actin cytoskeleton through CORO1A.Downregulation of CORO1A gene transcription restricts entry/survival of mycobacteria within macrophages
• Uniprot ID: Q2YD73
• Protein Accession #: NP_009005
• Nucleotide Accession #: NM_007074
• Protein Size (# AA): 461
• Molecular Weight: 51kDa
• Protein Interactions: FSD2; GOLGA2; UBC; YTHDC1; SPATA20; POT1; TAB1; GIT2; POLR1C; STAT3; SMARCD1; MAGOH; SMAD3; LMO2; FHL3; FMNL1; NCF4; THBS1; ACTB; DKK1; UBE2G2;