CORIN Recombinant Protein (OPCD02427)

Catalog No: OPCD02427

CORIN Recombinant Protein (OPCD02427) using SDS-PAGE

CORIN Recombinant Protein (OPCD02427) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Thr807-Thr1038
  Subcellular Location: Cell membrane; Single-pass type II membrane prote
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His and GST Tag

Target Info

• Gene Symbol: CORIN
• Gene Full Name: corin, serine peptidase
• Alias Symbols: ATC2;atrial natriuretic peptide-converting enzyme;Corin;CRN;heart-specific serine proteinase ATC2;Lrp4;PEE5;pro-ANP-convertase;pro-ANP-converting enzyme;TMPRSS10;transmembrane protease serine 10.
• NCBI Gene Id: 10699
• Protein Name: Atrial natriuretic peptide-converting enzyme
• Description of Target: Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide.
• Uniprot ID: Q9Y5Q5
• Protein Accession #: NP_001265514.1
• Nucleotide Accession #: NM_001278585.1
• Protein Size (# AA): Thr807~Thr1038
• Molecular Weight: 56kDa